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Engineering of temperature- and light-switchable Cas9 variants

Sensory photoreceptors have enabled non-invasive and spatiotemporal control of numerous biological processes. Photoreceptor engineering has expanded the repertoire beyond natural receptors, but to date no generally applicable strategy exists towards constructing light-regulated protein actuators of...

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Detalles Bibliográficos
Autores principales: Richter, Florian, Fonfara, Ines, Bouazza, Boris, Schumacher, Charlotte Helene, Bratovič, Majda, Charpentier, Emmanuelle, Möglich, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5175372/
https://www.ncbi.nlm.nih.gov/pubmed/27744350
http://dx.doi.org/10.1093/nar/gkw930