Splice variant insertions in the C-terminus impairs YAP’s transactivation domain

The yes-associated protein (YAP) is a key effector of the mammalian Hippo signaling pathway. YAP has eight known alternately spliced isoforms and these are widely expressed across multiple tissues. Variable effects have been ascribed to different YAP isoforms by inducing their expression in cells, b...

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Detalles Bibliográficos
Autores principales: Finch-Edmondson, Megan L., Strauss, Robyn P., Clayton, Joshua S., Yeoh, George C., Callus, Bernard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176130/
https://www.ncbi.nlm.nih.gov/pubmed/28018981
http://dx.doi.org/10.1016/j.bbrep.2016.02.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176130/
https://www.ncbi.nlm.nih.gov/pubmed/28018981
http://dx.doi.org/10.1016/j.bbrep.2016.02.015

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