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Splice variant insertions in the C-terminus impairs YAP’s transactivation domain
The yes-associated protein (YAP) is a key effector of the mammalian Hippo signaling pathway. YAP has eight known alternately spliced isoforms and these are widely expressed across multiple tissues. Variable effects have been ascribed to different YAP isoforms by inducing their expression in cells, b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176130/ https://www.ncbi.nlm.nih.gov/pubmed/28018981 http://dx.doi.org/10.1016/j.bbrep.2016.02.015 |