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Investigating the Potential Signaling Pathways That Regulate Activation of the Novel PKC Downstream of Serotonin in Aplysia

Activation of the novel PKC Apl II in sensory neurons by serotonin (5HT) underlies the ability of 5HT to reverse synaptic depression, but the pathway from 5HT to PKC Apl II activation remains unclear. Here we find no evidence for the Aplysia-specific B receptors, or for adenylate cyclase activation,...

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Detalles Bibliográficos
Autores principales: Farah, Carole A., Rourke, Bryan, Shin, Unkyung, Ferguson, Larissa, Luna, María José, Sossin, Wayne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176290/
https://www.ncbi.nlm.nih.gov/pubmed/28002451
http://dx.doi.org/10.1371/journal.pone.0168411