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Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice
BACKGROUND AND AIMS: The impairment of intestinal epithelial barrier is the main etiologic factor of inflammatory bowel disease. The proper intestinal epithelial proliferation and differentiation is crucial for maintaining intestinal integrity. Metformin is a common anti-diabetic drug. The objective...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176295/ https://www.ncbi.nlm.nih.gov/pubmed/28002460 http://dx.doi.org/10.1371/journal.pone.0168670 |