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Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice

BACKGROUND AND AIMS: The impairment of intestinal epithelial barrier is the main etiologic factor of inflammatory bowel disease. The proper intestinal epithelial proliferation and differentiation is crucial for maintaining intestinal integrity. Metformin is a common anti-diabetic drug. The objective...

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Detalles Bibliográficos
Autores principales: Xue, Yansong, Zhang, Hanying, Sun, Xiaofei, Zhu, Mei-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176295/
https://www.ncbi.nlm.nih.gov/pubmed/28002460
http://dx.doi.org/10.1371/journal.pone.0168670