Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members

Lysine acetylation has emerged as a dominant post-translational modification (PTM) regulating tau proteins in Alzheimer’s disease (AD) and related tauopathies. Mass spectrometry studies indicate that tau acetylation sites cluster within the microtubule-binding region (MTBR), a region that is highly...

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Detalles Bibliográficos
Autores principales: Hwang, Andrew W., Trzeciakiewicz, Hanna, Friedmann, Dave, Yuan, Chao-Xing, Marmorstein, Ronen, Lee, Virginia M. Y., Cohen, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176320/
https://www.ncbi.nlm.nih.gov/pubmed/28002468
http://dx.doi.org/10.1371/journal.pone.0168913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176320/
https://www.ncbi.nlm.nih.gov/pubmed/28002468
http://dx.doi.org/10.1371/journal.pone.0168913

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