A Combinatory Antibody–Antigen Microarray Assay for High-Content Screening of Single-Chain Fragment Variable Clones from Recombinant Libraries

We have developed a combinatory antibody–antigen microarray for direct screening of multiple single-chain fragment variable (scFv) clones with no need for pre-purification or enrichment before screening. The straightforward workflow allows for early selection of binders to predefined peptide and gly...

Descripción completa

Detalles Bibliográficos
Autores principales: Persson, Nina, Jansson, Bo, Stuhr-Hansen, Nicolai, Kovács, András, Welinder, Charlotte, Danielsson, Lena, Blixt, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176327/
https://www.ncbi.nlm.nih.gov/pubmed/28002485
http://dx.doi.org/10.1371/journal.pone.0168761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176327/
https://www.ncbi.nlm.nih.gov/pubmed/28002485
http://dx.doi.org/10.1371/journal.pone.0168761

Ejemplares similares