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A Combinatory Antibody–Antigen Microarray Assay for High-Content Screening of Single-Chain Fragment Variable Clones from Recombinant Libraries

We have developed a combinatory antibody–antigen microarray for direct screening of multiple single-chain fragment variable (scFv) clones with no need for pre-purification or enrichment before screening. The straightforward workflow allows for early selection of binders to predefined peptide and gly...

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Detalles Bibliográficos
Autores principales:	Persson, Nina, Jansson, Bo, Stuhr-Hansen, Nicolai, Kovács, András, Welinder, Charlotte, Danielsson, Lena, Blixt, Ola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176327/ https://www.ncbi.nlm.nih.gov/pubmed/28002485 http://dx.doi.org/10.1371/journal.pone.0168761

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