Cargando…

An essential cell-autonomous role for hepcidin in cardiac iron homeostasis

Hepcidin is the master regulator of systemic iron homeostasis. Derived primarily from the liver, it inhibits the iron exporter ferroportin in the gut and spleen, the sites of iron absorption and recycling respectively. Recently, we demonstrated that ferroportin is also found in cardiomyocytes, and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Lakhal-Littleton, Samira, Wolna, Magda, Chung, Yu Jin, Christian, Helen C, Heather, Lisa C, Brescia, Marcella, Ball, Vicky, Diaz, Rebeca, Santos, Ana, Biggs, Daniel, Clarke, Kieran, Davies, Benjamin, Robbins, Peter A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176354/
https://www.ncbi.nlm.nih.gov/pubmed/27897970
http://dx.doi.org/10.7554/eLife.19804