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EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis

Entamoeba histolytica, the highly phagocytic protozoan causative of human amoebiasis lacks the machinery to synthesize cholesterol. Here, we investigated the presence of NPC1 and NPC2 proteins in this parasite, which are involved in cholesterol trafficking in mammals. Bioinformatics analysis reveale...

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Detalles Bibliográficos
Autores principales: Bolaños, Jeni, Betanzos, Abigail, Javier-Reyna, Rosario, García- Rivera, Guillermina, Huerta, Miriam, Pais-Morales, Jonnatan, González-Robles, Arturo, Rodríguez, Mario A., Schnoor, Michael, Orozco, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176366/
https://www.ncbi.nlm.nih.gov/pubmed/28002502
http://dx.doi.org/10.1371/journal.ppat.1006089