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EhNPC1 and EhNPC2 Proteins Participate in Trafficking of Exogenous Cholesterol in Entamoeba histolytica Trophozoites: Relevance for Phagocytosis
Entamoeba histolytica, the highly phagocytic protozoan causative of human amoebiasis lacks the machinery to synthesize cholesterol. Here, we investigated the presence of NPC1 and NPC2 proteins in this parasite, which are involved in cholesterol trafficking in mammals. Bioinformatics analysis reveale...
Autores principales: | Bolaños, Jeni, Betanzos, Abigail, Javier-Reyna, Rosario, García- Rivera, Guillermina, Huerta, Miriam, Pais-Morales, Jonnatan, González-Robles, Arturo, Rodríguez, Mario A., Schnoor, Michael, Orozco, Esther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176366/ https://www.ncbi.nlm.nih.gov/pubmed/28002502 http://dx.doi.org/10.1371/journal.ppat.1006089 |
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