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Exonuclease activity and P nucleotide addition in the generation of the expressed immunoglobulin repertoire
BACKGROUND: Immunoglobulin rearrangement involves random and imprecise processes that act to both create and constrain diversity. Two such processes are the loss of nucleotides through the action of unknown exonuclease(s) and the addition of P nucleotides. The study of such processes has been compro...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517710/ https://www.ncbi.nlm.nih.gov/pubmed/15345030 http://dx.doi.org/10.1186/1471-2172-5-19 |