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Exonuclease activity and P nucleotide addition in the generation of the expressed immunoglobulin repertoire

BACKGROUND: Immunoglobulin rearrangement involves random and imprecise processes that act to both create and constrain diversity. Two such processes are the loss of nucleotides through the action of unknown exonuclease(s) and the addition of P nucleotides. The study of such processes has been compro...

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Detalles Bibliográficos
Autores principales: Jackson, Katherine JL, Gaeta, Bruno, Sewell, William, Collins, Andrew M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517710/
https://www.ncbi.nlm.nih.gov/pubmed/15345030
http://dx.doi.org/10.1186/1471-2172-5-19