FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3

FOXA1 is a pioneer factor that binds to enhancer regions that are enriched in H3K4 mono- and dimethylation (H3K4me1 and H3K4me2). We performed a FOXA1 rapid immunoprecipitation mass spectrometry of endogenous proteins (RIME) screen in ERα-positive MCF-7 breast cancer cells and found histone-lysine N...

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Detalles Bibliográficos
Autores principales: Jozwik, Kamila M., Chernukhin, Igor, Serandour, Aurelien A., Nagarajan, Sankari, Carroll, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177601/
https://www.ncbi.nlm.nih.gov/pubmed/27926873
http://dx.doi.org/10.1016/j.celrep.2016.11.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177601/
https://www.ncbi.nlm.nih.gov/pubmed/27926873
http://dx.doi.org/10.1016/j.celrep.2016.11.028

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