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Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis

Cytokinesis, the final step of cell division, begins with the formation of a cleavage furrow. How the mitotic spindle specifies the furrow at the equator in animal cells remains unknown. Current models propose that the concentration of the RhoGEF ECT2 at the spindle midzone and the equatorial plasma...

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Detalles Bibliográficos
Autores principales: Kotýnková, Kristýna, Su, Kuan-Chung, West, Stephen C., Petronczki, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177604/
https://www.ncbi.nlm.nih.gov/pubmed/27926870
http://dx.doi.org/10.1016/j.celrep.2016.11.029