In vivo functional dissection of a context-dependent role for Hif1α in pancreatic tumorigenesis

Hypoxia-inducible factor 1α (Hif1α) is a key regulator of cellular adaptation and survival under hypoxic conditions. In pancreatic ductal adenocarcinoma (PDAC), it has been recently shown that genetic ablation of Hif1α accelerates tumour development by promoting tumour-supportive inflammation in mic...

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Detalles Bibliográficos
Autores principales: Cheng, T, Jian, Z, Li, K, Raulefs, S, Regel, I, Shen, S, Zou, X, Ruland, J, Ceyhan, G O, Friess, H, Michalski, C W, Kleeff, J, Kong, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177776/
https://www.ncbi.nlm.nih.gov/pubmed/27941931
http://dx.doi.org/10.1038/oncsis.2016.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177776/
https://www.ncbi.nlm.nih.gov/pubmed/27941931
http://dx.doi.org/10.1038/oncsis.2016.78

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