Angiotensin II increases glomerular permeability by β-arrestin mediated nephrin endocytosis

Glomerular permeability and subsequent albuminuria are early clinical markers for glomerular injury in hypertensive nephropathy. Albuminuria predicts mortality and cardiovascular morbidity. AT1 receptor blockers protect from albuminuria, cardiovascular morbidity and mortality. A blood pressure indep...

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Detalles Bibliográficos
Autores principales: Königshausen, Eva, Zierhut, Ulf M., Ruetze, Martin, Potthoff, Sebastian A., Stegbauer, Johannes, Woznowski, Magdalena, Quack, Ivo, Rump, Lars C., Sellin, Lorenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177899/
https://www.ncbi.nlm.nih.gov/pubmed/28004760
http://dx.doi.org/10.1038/srep39513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177899/
https://www.ncbi.nlm.nih.gov/pubmed/28004760
http://dx.doi.org/10.1038/srep39513

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