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Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences
There are hundreds of ligands which can interact with G-quadruplex DNA, yet very few which target i-motif. To appreciate an understanding between the dynamics between these structures and how they can be affected by intervention with small molecule ligands, more i-motif binding compounds are require...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177923/ https://www.ncbi.nlm.nih.gov/pubmed/28004744 http://dx.doi.org/10.1038/srep39456 |