Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences

There are hundreds of ligands which can interact with G-quadruplex DNA, yet very few which target i-motif. To appreciate an understanding between the dynamics between these structures and how they can be affected by intervention with small molecule ligands, more i-motif binding compounds are require...

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Detalles Bibliográficos
Autores principales: Wright, Elisé P., Day, Henry A., Ibrahim, Ali M., Kumar, Jeethendra, Boswell, Leo J. E., Huguin, Camille, Stevenson, Clare E. M., Pors, Klaus, Waller, Zoë A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177923/
https://www.ncbi.nlm.nih.gov/pubmed/28004744
http://dx.doi.org/10.1038/srep39456

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