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IL-13 is a therapeutic target in radiation lung injury

Pulmonary fibrosis is a potentially lethal late adverse event of thoracic irradiation. Prior research indicates that unrestrained TGF-β1 and/or type 2 cytokine-driven immune responses promote fibrosis following radiation injury, but the full spectrum of factors governing this pathology remains uncle...

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Detalles Bibliográficos
Autores principales: Chung, Su I., Horton, Jason A., Ramalingam, Thirumalai R., White, Ayla O., Chung, Eun Joo, Hudak, Kathryn E., Scroggins, Bradley T., Arron, Joseph R., Wynn, Thomas A., Citrin, Deborah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177927/
https://www.ncbi.nlm.nih.gov/pubmed/28004808
http://dx.doi.org/10.1038/srep39714