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IL-13 is a therapeutic target in radiation lung injury
Pulmonary fibrosis is a potentially lethal late adverse event of thoracic irradiation. Prior research indicates that unrestrained TGF-β1 and/or type 2 cytokine-driven immune responses promote fibrosis following radiation injury, but the full spectrum of factors governing this pathology remains uncle...
Autores principales: | Chung, Su I., Horton, Jason A., Ramalingam, Thirumalai R., White, Ayla O., Chung, Eun Joo, Hudak, Kathryn E., Scroggins, Bradley T., Arron, Joseph R., Wynn, Thomas A., Citrin, Deborah E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177927/ https://www.ncbi.nlm.nih.gov/pubmed/28004808 http://dx.doi.org/10.1038/srep39714 |
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