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Tauroursodeoxycholic acid reduces ER stress by regulating of Akt-dependent cellular prion protein

Although mesenchymal stem cells (MSCs) are a promising cell source for regenerative medicine, ischemia-induced endoplasmic reticulum (ER) stress induces low MSC engraftment and limits their therapeutic efficacy. To overcome this, we investigated the protective effect of tauroursodeoxycholic acid (TU...

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Detalles Bibliográficos
Autores principales: Yoon, Yeo Min, Lee, Jun Hee, Yun, Seung Pil, Han, Yong-Seok, Yun, Chul Won, Lee, Hyun Jik, Noh, Hyunjin, Lee, Sei-Jung, Han, Ho Jae, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177936/
https://www.ncbi.nlm.nih.gov/pubmed/28004805
http://dx.doi.org/10.1038/srep39838