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Analysis of CXCR5(+)Th17 cells in relation to disease activity and TNF inhibitor therapy in Rheumatoid Arthritis

Th17 and TfH cells are thought to promote tissue inflammation and autoantibody production, respectively, in autoimmune diseases including rheumatoid arthritis (RA). TfH cells that co-express Th17 markers (CXCR5(+)Th17) encompass both of these pathogenic functions, and are increased in some human aut...

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Detalles Bibliográficos
Autores principales: Singh, Deepika, Henkel, Matthew, Sendon, Bernadette, Feng, June, Fabio, Anthony, Metes, Diana, Moreland, Larry W., McGeachy, Mandy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177940/
https://www.ncbi.nlm.nih.gov/pubmed/28004828
http://dx.doi.org/10.1038/srep39474