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Alteration of platelet GPVI signaling in ST-elevation myocardial infarction patients demonstrated by a combination of proteomic, biochemical, and functional approaches

The platelet-specific collagen receptor glycoprotein VI (GPVI) is critical for the formation of arterial thrombosis in vivo. We analyzed GPVI-activated platelets from ST-elevation myocardial infarction (STEMI) patients and matched stable coronary artery disease (SCAD) controls in order to provide no...

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Detalles Bibliográficos
Autores principales: Vélez, Paula, Ocaranza-Sánchez, Raymundo, López-Otero, Diego, Grigorian-Shamagian, Lilian, Rosa, Isaac, Guitián, Esteban, García-Acuña, José María, González-Juanatey, José Ramón, García, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177944/
https://www.ncbi.nlm.nih.gov/pubmed/28004756
http://dx.doi.org/10.1038/srep39603