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Fluid flow facilitates inward rectifier K(+) current by convectively restoring [K(+)] at the cell membrane surface

The inward rectifier Kir2.1 current (IKir2.1) was reported to be facilitated by fluid flow. However, the mechanism underlying this facilitation remains uncertain. We hypothesized that during K(+) influx or efflux, [K(+)] adjacent to the outer mouth of the Kir2.1 channel might decrease or increase, r...

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Detalles Bibliográficos
Autores principales: Kim, Jae Gon, Park, Sang Woong, Byun, Doyoung, Choi, Wahn Soo, Sung, Dong Jun, Shin, Kyung Chul, Kim, Hyun-ji, Leem, Young-Eun, Kang, Jong-Sun, Cho, Hana, Kim, Bokyung, Cho, Sung I, Bae, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177964/
https://www.ncbi.nlm.nih.gov/pubmed/28004830
http://dx.doi.org/10.1038/srep39585