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Effects of whole genome duplication on cell size and gene expression in mouse embryonic stem cells

Alterations in ploidy tend to influence cell physiology, which in the long-term, contribute to species adaptation and evolution. Polyploid cells are observed under physiological conditions in the nerve and liver tissues, and in tumorigenic processes. Although tetraploid cells have been studied in ma...

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Detalles Bibliográficos
Autores principales: IMAI, Hiroyuki, FUJII, Wataru, KUSAKABE, Ken Takeshi, KISO, Yasuo, KANO, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177974/
https://www.ncbi.nlm.nih.gov/pubmed/27569766
http://dx.doi.org/10.1262/jrd.2016-037