FMRP Expression Levels in Mouse Central Nervous System Neurons Determine Behavioral Phenotype

Fragile X mental retardation protein (FMRP) is absent or highly reduced in Fragile X Syndrome, a genetic disorder causing cognitive impairment and autistic behaviors. Previous proof-of-principle studies have demonstrated that restoring FMRP in the brain using viral vectors can improve pathological a...

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Detalles Bibliográficos
Autores principales: Arsenault, Jason, Gholizadeh, Shervin, Niibori, Yosuke, Pacey, Laura K., Halder, Sebok K., Koxhioni, Enea, Konno, Ayumu, Hirai, Hirokazu, Hampson, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178026/
https://www.ncbi.nlm.nih.gov/pubmed/27604541
http://dx.doi.org/10.1089/hum.2016.090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178026/
https://www.ncbi.nlm.nih.gov/pubmed/27604541
http://dx.doi.org/10.1089/hum.2016.090

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