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The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs

BACKGROUND: The emergence of resistance to anti-tuberculosis drugs is a serious and growing threat to public health. Next-generation sequencing is rapidly gaining traction as a diagnostic tool for investigating drug resistance in Mycobacterium tuberculosis to aid treatment decisions. However, there...

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Detalles Bibliográficos
Autores principales: Phelan, Jody, O’Sullivan, Denise M., Machado, Diana, Ramos, Jorge, Whale, Alexandra S., O’Grady, Justin, Dheda, Keertan, Campino, Susana, McNerney, Ruth, Viveiros, Miguel, Huggett, Jim F., Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178084/
https://www.ncbi.nlm.nih.gov/pubmed/28003022
http://dx.doi.org/10.1186/s13073-016-0385-x