Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice

Piwi-interacting RNAs (piRNAs) are a class of small noncoding RNAs. piRNAs protect the genome integrity of the germline by silencing active transposable elements and are essential for germ cell development. Most piRNA pathway proteins are evolutionarily conserved. MOV10L1, a testis-specific RNA heli...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Qi, Pandey, Radha Raman, Leu, N. Adrian, Pillai, Ramesh S., Wang, P. Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178147/
https://www.ncbi.nlm.nih.gov/pubmed/27655786
http://dx.doi.org/10.1095/biolreprod.116.142430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178147/
https://www.ncbi.nlm.nih.gov/pubmed/27655786
http://dx.doi.org/10.1095/biolreprod.116.142430

Ejemplares similares