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Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea

Translation initiation factor 5A (IF5A) is essential and highly conserved in Eukarya (eIF5A) and Archaea (aIF5A). The activity of IF5A requires hypusine, a posttranslational modification synthesized in Eukarya from the polyamine precursor spermidine. Intracellular polyamine analyses revealed that ag...

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Detalles Bibliográficos
Autores principales: Prunetti, Laurence, Graf, Michael, Blaby, Ian K., Peil, Lauri, Makkay, Andrea M., Starosta, Agata L., Papke, R. Thane, Oshima, Tairo, Wilson, Daniel N., de Crécy-Lagard, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178350/
https://www.ncbi.nlm.nih.gov/pubmed/28053595
http://dx.doi.org/10.1155/2016/7316725