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Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea
Translation initiation factor 5A (IF5A) is essential and highly conserved in Eukarya (eIF5A) and Archaea (aIF5A). The activity of IF5A requires hypusine, a posttranslational modification synthesized in Eukarya from the polyamine precursor spermidine. Intracellular polyamine analyses revealed that ag...
Autores principales: | Prunetti, Laurence, Graf, Michael, Blaby, Ian K., Peil, Lauri, Makkay, Andrea M., Starosta, Agata L., Papke, R. Thane, Oshima, Tairo, Wilson, Daniel N., de Crécy-Lagard, Valérie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178350/ https://www.ncbi.nlm.nih.gov/pubmed/28053595 http://dx.doi.org/10.1155/2016/7316725 |
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