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Glibenclamide Prevents Diabetes in NOD Mice

Previous work has revealed that Cx36, the sole connexin expressed in the insulin-producing beta cells, enhances the secretion of insulin, and promotes the resistance of beta cells against pro-inflammatory cytokines. In parallel, the anti-diabetic sulphonylurea glibenclamide was shown to promote the...

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Detalles Bibliográficos
Autores principales: Lamprianou, Smaragda, Gysemans, Conny, Bou Saab, Joanna, Pontes, Helena, Mathieu, Chantal, Meda, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178991/
https://www.ncbi.nlm.nih.gov/pubmed/28006000
http://dx.doi.org/10.1371/journal.pone.0168839