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The Central Role of KNG1 Gene as a Genetic Determinant of Coagulation Pathway-Related Traits: Exploring Metaphenotypes

Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce an original methodology to analyze sets of correlated phen...

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Detalles Bibliográficos
Autores principales: Brunel, Helena, Massanet, Raimon, Martinez-Perez, Angel, Ziyatdinov, Andrey, Martin-Fernandez, Laura, Souto, Juan Carlos, Perera, Alexandre, Soria, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178993/
https://www.ncbi.nlm.nih.gov/pubmed/28005926
http://dx.doi.org/10.1371/journal.pone.0167187