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Selection and Characterization of Tau Binding ᴅ-Enantiomeric Peptides with Potential for Therapy of Alzheimer Disease

A variety of neurodegenerative disorders, including Alzheimer disease (AD), are associated with neurofibrillary tangles composed of the tau protein, as well as toxic tau oligomers. Inhibitors of pathological tau aggregation, interrupting tau self-assembly, might be useful for the development of ther...

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Detalles Bibliográficos
Autores principales: Dammers, Christina, Yolcu, Deniz, Kukuk, Laura, Willbold, Dieter, Pickhardt, Marcus, Mandelkow, Eckhard, Horn, Anselm H. C., Sticht, Heinrich, Malhis, Marwa Nidal, Will, Nadja, Schuster, Judith, Funke, Susanne Aileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179029/
https://www.ncbi.nlm.nih.gov/pubmed/28006031
http://dx.doi.org/10.1371/journal.pone.0167432