The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis

The mitochondrial permeability transition pore (mPTP) is a key regulator of mitochondrial function that has been implicated in the pathogenesis of metabolic disease. Cyclophilin D (CypD) is a critical regulator that directly binds to mPTP constituents to facilitate the pore opening. We previously fo...

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Detalles Bibliográficos
Autores principales: Laker, Rhianna C., Taddeo, Evan P., Akhtar, Yasir N., Zhang, Mei, Hoehn, Kyle L., Yan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179060/
https://www.ncbi.nlm.nih.gov/pubmed/28005946
http://dx.doi.org/10.1371/journal.pone.0167910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179060/
https://www.ncbi.nlm.nih.gov/pubmed/28005946
http://dx.doi.org/10.1371/journal.pone.0167910

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