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The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis
The mitochondrial permeability transition pore (mPTP) is a key regulator of mitochondrial function that has been implicated in the pathogenesis of metabolic disease. Cyclophilin D (CypD) is a critical regulator that directly binds to mPTP constituents to facilitate the pore opening. We previously fo...
Autores principales: | Laker, Rhianna C., Taddeo, Evan P., Akhtar, Yasir N., Zhang, Mei, Hoehn, Kyle L., Yan, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179060/ https://www.ncbi.nlm.nih.gov/pubmed/28005946 http://dx.doi.org/10.1371/journal.pone.0167910 |
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