Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1

Given the frequent misregulation of chromatin in cancer, it is important to understand the cellular mechanisms that regulate chromatin structure. However, systematic screening for epigenetic regulators is challenging and often relies on laborious assays or indirect reporter read-outs. Here we descri...

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Detalles Bibliográficos
Autores principales: Vlaming, Hanneke, Molenaar, Thom M, van Welsem, Tibor, Poramba-Liyanage, Deepani W, Smith, Desiree E, Velds, Arno, Hoekman, Liesbeth, Korthout, Tessy, Hendriks, Sjoerd, Maarten Altelaar, AF, van Leeuwen, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179194/
https://www.ncbi.nlm.nih.gov/pubmed/27922451
http://dx.doi.org/10.7554/eLife.18919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179194/
https://www.ncbi.nlm.nih.gov/pubmed/27922451
http://dx.doi.org/10.7554/eLife.18919

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