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Establishment of a 3D In Vitro Model to Accelerate the Development of Human Therapies against Corneal Diabetes
PURPOSE: To establish an in vitro model that would mirror the in vivo corneal stromal environment in diabetes (DM) patients. METHODS: Human corneal fibroblasts from Healthy (HCFs), Type 1DM (T1DM) and Type 2DM (T2DM) donors were isolated and cultured for 4 weeks with Vitamin C stimulation in order t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179241/ https://www.ncbi.nlm.nih.gov/pubmed/28005998 http://dx.doi.org/10.1371/journal.pone.0168845 |