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An Automated Image Analysis System to Quantify Endosomal Tubulation

Recycling of cargos from early endosomes requires regulation of endosomal tubule formation and fission. This regulation is disrupted in cells depleted of the microtubule severing enzyme spastin, causing elongation of endosomal tubules and mis-trafficking of recycling endosomal cargos such as the tra...

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Detalles Bibliográficos
Autores principales: Newton, Timothy M., Reid, Evan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179261/
https://www.ncbi.nlm.nih.gov/pubmed/28006827
http://dx.doi.org/10.1371/journal.pone.0168294