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Co-administration of a DNA vaccine encoding the prostate specific membrane antigen and CpG oligodeoxynucleotides suppresses tumor growth

BACKGROUND: Prostate-specific membrane antigen (PSMA) is a well characterized prostate-specific tumor associated antigen. Its expression is elevated in prostate carcinoma, particularly in metastatic and recurrent lesions. These observations suggest that PSMA can be used as immune target to induce tu...

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Detalles Bibliográficos
Autores principales: Ren, Jiaqiang, Zheng, Li, Chen, Qi, Li, Hua, Zhang, Lin, Zhu, Hongguang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517950/
https://www.ncbi.nlm.nih.gov/pubmed/15357867
http://dx.doi.org/10.1186/1479-5876-2-29