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Ambiguous allele combinations in HLA Class I and Class II sequence-based typing: when precise nucleotide sequencing leads to imprecise allele identification

Sequence-based typing (SBT) is one of the most comprehensive methods utilized for HLA typing. However, one of the inherent problems with this typing method is the interpretation of ambiguous allele combinations which occur when two or more different allele combinations produce identical sequences. T...

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Detalles Bibliográficos
Autores principales: Adams, Sharon D, Barracchini, Kathleen C, Chen, Deborah, Robbins, FuMeei, Wang, Lu, Larsen, Paula, Luhm, Robert, Stroncek, David F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC517951/
https://www.ncbi.nlm.nih.gov/pubmed/15363110
http://dx.doi.org/10.1186/1479-5876-2-30