Identification of plexin A4 as a novel clusterin receptor links two Alzheimer’s disease risk genes

Although abundant genetic and biochemical evidence strongly links Clusterin (CLU) to Alzheimer disease (AD) pathogenesis, the receptor for CLU within the adult brain is currently unknown. Using unbiased approaches, we identified Plexin A4 (PLXNA4) as a novel, high-affinity receptor for CLU in the ad...

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Detalles Bibliográficos
Autores principales: Kang, Silvia S., Kurti, Aishe, Wojtas, Aleksandra, Baker, Kelsey E., Liu, Chia-Chen, Kanekiyo, Takahisa, Deming, Yuetiva, Cruchaga, Carlos, Estus, Steven, Bu, Guojun, Fryer, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179943/
https://www.ncbi.nlm.nih.gov/pubmed/27378688
http://dx.doi.org/10.1093/hmg/ddw188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179943/
https://www.ncbi.nlm.nih.gov/pubmed/27378688
http://dx.doi.org/10.1093/hmg/ddw188

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