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Genetic ablation of IP(3) receptor 2 increases cytokines and decreases survival of SOD1(G93A) mice
Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease characterized by the selective death of motor neurons. Disease pathophysiology is complex and not yet fully understood. Higher gene expression of the inositol 1,4,5-trisphosphate receptor 2 gene (ITPR2), encod...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179944/ https://www.ncbi.nlm.nih.gov/pubmed/27378687 http://dx.doi.org/10.1093/hmg/ddw190 |