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Zika virus infection induces mitosis abnormalities and apoptotic cell death of human neural progenitor cells

Zika virus (ZIKV) infection has been associated with severe complications both in the developing and adult nervous system. To investigate the deleterious effects of ZIKV infection, we used human neural progenitor cells (NPC), derived from induced pluripotent stem cells (iPSC). We found that NPC are...

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Detalles Bibliográficos
Autores principales: Souza, Bruno S. F., Sampaio, Gabriela L. A., Pereira, Ciro S., Campos, Gubio S., Sardi, Silvia I., Freitas, Luiz A. R., Figueira, Claudio P., Paredes, Bruno D., Nonaka, Carolina K. V., Azevedo, Carine M., Rocha, Vinicius P. C., Bandeira, Antonio C., Mendez-Otero, Rosalia, dos Santos, Ricardo Ribeiro, Soares, Milena B. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180086/
https://www.ncbi.nlm.nih.gov/pubmed/28008958
http://dx.doi.org/10.1038/srep39775