Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins

Compiling a comprehensive list of cancer driver genes is imperative for oncology diagnostics and drug development. While driver genes are typically discovered by analysis of tumor genomes, infrequently mutated driver genes often evade detection due to limited sample sizes. Here, we address sample si...

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Detalles Bibliográficos
Autores principales: Waks, Zeev, Weissbrod, Omer, Carmeli, Boaz, Norel, Raquel, Utro, Filippo, Goldschmidt, Yaara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180091/
https://www.ncbi.nlm.nih.gov/pubmed/28008934
http://dx.doi.org/10.1038/srep38988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180091/
https://www.ncbi.nlm.nih.gov/pubmed/28008934
http://dx.doi.org/10.1038/srep38988

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