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Drosophila microRNA-34 Impairs Axon Pruning of Mushroom Body γ Neurons by Downregulating the Expression of Ecdysone Receptor

MicroRNA-34 (miR-34) is crucial for preventing chronic large-scale neurite degeneration in the aged brain of Drosophila melanogaster. Here we investigated the role of miR-34 in two other types of large-scale axon degeneration in Drosophila: axotomy-induced axon degeneration in olfactory sensory neur...

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Detalles Bibliográficos
Autores principales: Lai, Yen-Wei, Chu, Sao-Yu, Wei, Jia-Yi, Cheng, Chu-Ya, Li, Jian-Chiuan, Chen, Po-Lin, Chen, Chun-Hong, Yu, Hung-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180235/
https://www.ncbi.nlm.nih.gov/pubmed/28008974
http://dx.doi.org/10.1038/srep39141