Self assembly of HIV-1 Gag protein on lipid membranes generates PI(4,5)P(2)/Cholesterol nanoclusters

The self-assembly of HIV-1 Gag polyprotein at the inner leaflet of the cell host plasma membrane is the key orchestrator of virus assembly. The binding between Gag and the plasma membrane is mediated by specific interaction of the Gag matrix domain and the PI(4,5)P(2) lipid (PIP(2)). It is unknown w...

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Detalles Bibliográficos
Autores principales: Yandrapalli, Naresh, Lubart, Quentin, Tanwar, Hanumant S., Picart, Catherine, Mak, Johnson, Muriaux, Delphine, Favard, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180241/
https://www.ncbi.nlm.nih.gov/pubmed/28008947
http://dx.doi.org/10.1038/srep39332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180241/
https://www.ncbi.nlm.nih.gov/pubmed/28008947
http://dx.doi.org/10.1038/srep39332

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