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Proteins adopt functionally active conformations after type III secretion

BACKGROUND: Bacterial production of natively folded heterologous proteins by secretion to the extracellular space can improve protein production by simplifying purification and enabling continuous processing. In a typical bacterial protein production process, the protein of interest accumulates in t...

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Detalles Bibliográficos
Autores principales: Metcalf, Kevin James, Bevington, James Lea, Rosales, Sandy Lisette, Burdette, Lisa Ann, Valdivia, Elias, Tullman-Ercek, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180411/
https://www.ncbi.nlm.nih.gov/pubmed/28010734
http://dx.doi.org/10.1186/s12934-016-0606-4