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Tocotrienols induce endoplasmic reticulum stress and apoptosis in cervical cancer cells

BACKGROUND: We have previously reported that γ- and δ-tocotrienols (γ- and δ-T3) induce gene expression and apoptosis in human breast cancer cells (MDA-MB-231 and MCF-7). This effect is mediated, at least in part, by a specific binding and activation of the estrogen receptor-β (ERβ). Transcriptomic...

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Detalles Bibliográficos
Autores principales: Comitato, Raffaella, Guantario, Barbara, Leoni, Guido, Nesaretnam, Kalanithi, Ronci, Maria Beatrice, Canali, Raffaella, Virgili, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180413/
https://www.ncbi.nlm.nih.gov/pubmed/28031751
http://dx.doi.org/10.1186/s12263-016-0543-1