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A profile-based method for identifying functional divergence of orthologous genes in bacterial genomes

Motivation: Next generation sequencing technologies have provided us with a wealth of information on genetic variation, but predicting the functional significance of this variation is a difficult task. While many comparative genomics studies have focused on gene flux and large scale changes, relativ...

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Detalles Bibliográficos
Autores principales: Wheeler, Nicole E., Barquist, Lars, Kingsley, Robert A., Gardner, Paul P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181535/
https://www.ncbi.nlm.nih.gov/pubmed/27503221
http://dx.doi.org/10.1093/bioinformatics/btw518