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A profile-based method for identifying functional divergence of orthologous genes in bacterial genomes
Motivation: Next generation sequencing technologies have provided us with a wealth of information on genetic variation, but predicting the functional significance of this variation is a difficult task. While many comparative genomics studies have focused on gene flux and large scale changes, relativ...
Autores principales: | Wheeler, Nicole E., Barquist, Lars, Kingsley, Robert A., Gardner, Paul P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181535/ https://www.ncbi.nlm.nih.gov/pubmed/27503221 http://dx.doi.org/10.1093/bioinformatics/btw518 |
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